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Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(α) pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells
A reduction in endogenously generated reactive oxygen species in vivo delays benzo(α)pyrene (BaP)-accelerated atherosclerosis, as revealed in hypercholesterolemic mice overexpressing Cu/Zn-superoxide dismutase (SOD) and/or catalase. To understand the molecular events involved in this protective acti...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846758/ https://ncbi.nlm.nih.gov/pubmed/19666105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.08.001 |
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