Mucins and Their Sugars. Critical Mediators of Hyperreactivity and Inflammation

Excessive mucus causes severe airflow obstruction in fatal asthma. It is also present in mild to moderate disease, but is poorly understood and treated. Mucus overproduction is associated with dysregulated expression of the mucins MUC5AC and MUC5B. Whereas increased MUC5AC is a consistent finding, M...

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Udgivet i:Ann Am Thorac Soc
Main Authors: Raclawska, Dorota S., Ttofali, Fani, Fletcher, Ashley A., Harper, Daniel N., Bochner, Bruce S., Janssen, William J., Evans, Christopher M.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2016
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015746/
https://ncbi.nlm.nih.gov/pubmed/27027967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201511-743MG
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