Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer

BACKGROUND: The androgen receptor splice variant-7 (AR-V7) has been implicated in the development of castration-resistant prostate cancer (CRPC) and resistance to abiraterone and enzalutamide. OBJECTIVE: To develop a validated assay for detection of AR-V7 protein in tumour tissue and determine its e...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Eur Urol
Main Authors: Welti, Jonathan, Rodrigues, Daniel Nava, Sharp, Adam, Sun, Shihua, Lorente, David, Riisnaes, Ruth, Figueiredo, Ines, Zafeiriou, Zafeiris, Rescigno, Pasquale, de Bono, Johann S., Plymate, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Science 2016
Assuntos:
Platinum Priority – Prostate Cancer
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015575/
https://ncbi.nlm.nih.gov/pubmed/27117751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2016.03.049
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares