Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)

BACKGROUND: Pigment epithelium‐derived factor (PEDF), which belongs to the noninhibitory serpin family, has shown the ability to stimulate several physiological processes, such as antiangiogenesis, anti‐inflammation, and antioxidation. In the present study, the effects of PEDF on contractility and c...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Lu, Peng, Zhang, Yi‐Qian, Zhang, Hao, Li, Yu‐Feng, Wang, Xiao‐Yu, Xu, Hao, Liu, Zhi‐Wei, Li, Lei, Dong, Hong‐Yan, Zhang, Zhong‐Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015364/
https://ncbi.nlm.nih.gov/pubmed/27413044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.003179
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