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Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin‐Deficient Hearts

BACKGROUND: Cardiomyopathy is a leading cause of mortality among Duchenne muscular dystrophy patients and lacks effective therapies. Phosphodiesterase type 5 is implicated in dystrophic pathology, and the phosphodiesterase type 5 inhibitor tadalafil has recently been studied in a clinical trial for...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Hammers, David W., Sleeper, Margaret M., Forbes, Sean C., Shima, Ai, Walter, Glenn A., Sweeney, H. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015305/
https://ncbi.nlm.nih.gov/pubmed/27506543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003911
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