Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle

Duchenne muscular dystrophy (DMD) is a devastating muscle disease characterized by progressive muscle deterioration and replacement with an aberrant fatty, fibrous matrix. Chronic upregulation of nuclear factor κB (NF-κB) is implicated as a driver of the dystrophic pathogenesis. Herein, 2 members of...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Hammers, David W., Sleeper, Margaret M., Forbes, Sean C., Coker, Cora C., Jirousek, Michael R., Zimmer, Michael, Walter, Glenn A., Sweeney, H. Lee
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161210/
https://ncbi.nlm.nih.gov/pubmed/28018975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90341
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky