Delayed Cardiomyopathy in Dystrophin Deficient mdx Mice Relies on Intrinsic Glutathione Resource

Oxidative stress contributes to the pathogenesis of Duchenne muscular dystrophy (DMD). Although they have been a model for DMD, mdx mice exhibit slowly developing cardiomyopathy. We hypothesized that disease process was delayed owing to the development of an adaptive mechanism against oxidative stre...

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Hauptverfasser: Khouzami, Lara, Bourin, Marie-Claude, Christov, Christo, Damy, Thibaud, Escoubet, Brigitte, Caramelle, Philippe, Perier, Magali, Wahbi, Karim, Meune, Christophe, Pavoine, Catherine, Pecker, Françoise
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928968/
https://ncbi.nlm.nih.gov/pubmed/20696779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090479
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