In vivo characterization of Linc-p21 reveals functional cis-regulatory DNA elements

The Linc-p21 locus, encoding a long non-coding RNA, plays an important role in p53 signalling, cell cycle regulation, and tumour suppression. However, despite extensive study, confusion exists regarding its mechanism of action: is activity driven by the transcript acting in trans, in cis, or by an u...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Groff, Abigail F, Sanchez-Gomez, Diana B, Soruco, Marcela ML, Gerhardinger, Chiara, Barutcu, A. Rasim, Li, Eric, Elcavage, Lara, Plana, Olivia, Sanchez, Lluvia V, Lee, James C, Sauvageau, Martin, Rinn, John L
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014909/
https://ncbi.nlm.nih.gov/pubmed/27524623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.050
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