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Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain

Histone lysine acylations play an important role in regulation of gene transcription in chromatin. Unlike histone acetyl-lysine, molecular recognition of recently identified crotonyl-lysine mark is much less understood. Here, we report that the YEATS domain of AF9 preferentially binds crotonyl-lysin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Structure
Main Authors: Zhang, Qiang, Zeng, Lei, Zhao, ChengCheng, Ju, Ying, Konuma, Tsuyoshi, Zhou, Ming-Ming
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014688/
https://ncbi.nlm.nih.gov/pubmed/27545619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.05.023
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