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Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain
Histone lysine acylations play an important role in regulation of gene transcription in chromatin. Unlike histone acetyl-lysine, molecular recognition of recently identified crotonyl-lysine mark is much less understood. Here, we report that the YEATS domain of AF9 preferentially binds crotonyl-lysin...
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| Veröffentlicht in: | Structure |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014688/ https://ncbi.nlm.nih.gov/pubmed/27545619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.05.023 |
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