Humanized Mouse Model of Mast Cell-Mediated Passive Cutaneous Anaphylaxis and Passive Systemic Anaphylaxis

BACKGROUND: Mast cells are a critical component of allergic responses in humans, and animal models that allow the in vivo investigation of their contribution to allergy and evaluation of new human-specific therapeutics are urgently needed. OBJECTIVE: We have developed a new humanized mouse model tha...

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Veröffentlicht in:J Allergy Clin Immunol
Hauptverfasser: Bryce, Paul J., Falahati, Rustom, Kenney, Laurie, Leung, John, Bebbington, Christopher, Tomasevic, Nenad, Krier, Rebecca A, Hsu, Chia-Lin, Shultz, Leonard D., Greiner, Dale L., Brehm, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014665/
https://ncbi.nlm.nih.gov/pubmed/27139822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.01.049
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