Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms

Eitemau Tebyg

• Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc
  gan: Stoddart, Angela, et al.
  Cyhoeddwyd: (2014)
• Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice
  gan: Stoddart, Angela, et al.
  Cyhoeddwyd: (2014)
• Genetic Pathways Leading to Therapy-Related Myeloid Neoplasms
  gan: Stoddart, Angela, et al.
  Cyhoeddwyd: (2011)
• Epistasis between TIFAB and miR-146a: neighboring genes in del(5q) myelodysplastic syndrome
  gan: Varney, ME, et al.
  Cyhoeddwyd: (2016)
• Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms
  gan: Stoddart, Angela, et al.
  Cyhoeddwyd: (2015)