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seqlm: an MDL based method for identifying differentially methylated regions in high density methylation array data

Motivation: One of the main goals of large scale methylation studies is to detect differentially methylated loci. One way is to approach this problem sitewise, i.e. to find differentially methylated positions (DMPs). However, it has been shown that methylation is regulated in longer genomic regions....

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Kolde, Raivo, Märtens, Kaspar, Lokk, Kaie, Laur, Sven, Vilo, Jaak
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013909/
https://ncbi.nlm.nih.gov/pubmed/27187204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw304
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