Induction maintenance with tumour necrosis factor-inhibitor combination therapy with discontinuation versus methotrexate monotherapy in early rheumatoid arthritis: a systematic review and meta-analysis of efficacy in randomised controlled trials

OBJECTIVE: To determine whether an induction-maintenance strategy of combined therapy (methotrexate (MTX)+tumour necrosis factor (TNF) inhibitor (TNFi)) followed by withdrawal of TNFi could yield better long-term results than a strategy with MTX monotherapy, since it is unclear if the benefits from...

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Detalles Bibliográficos
Publicado en:RMD Open
Main Authors: Emamikia, Sharzad, Arkema, Elizabeth V, Györi, Noémi, Detert, Jacqueline, Chatzidionysiou, Katerina, Dougados, Maxime, Burmester, Gerd Rüdiger, van Vollenhoven, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2016
Assuntos:
Rheumatoid Arthritis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013458/
https://ncbi.nlm.nih.gov/pubmed/27651929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000323
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