aroA-Deficient Salmonella enterica Serovar Typhimurium Is More Than a Metabolically Attenuated Mutant

Recombinant attenuated Salmonella enterica serovar Typhimurium strains are believed to act as powerful live vaccine carriers that are able to elicit protection against various pathogens. Auxotrophic mutations, such as a deletion of aroA, are commonly introduced into such bacteria for attenuation wit...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Felgner, Sebastian, Frahm, Michael, Kocijancic, Dino, Rohde, Manfred, Eckweiler, Denitsa, Bielecka, Agata, Bueno, Emilio, Cava, Felipe, Abraham, Wolf-Rainer, Curtiss, Roy, Häussler, Susanne, Erhardt, Marc, Weiss, Siegfried
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013297/
https://ncbi.nlm.nih.gov/pubmed/27601574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01220-16
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