aroA-Deficient Salmonella enterica Serovar Typhimurium Is More Than a Metabolically Attenuated Mutant

Recombinant attenuated Salmonella enterica serovar Typhimurium strains are believed to act as powerful live vaccine carriers that are able to elicit protection against various pathogens. Auxotrophic mutations, such as a deletion of aroA, are commonly introduced into such bacteria for attenuation wit...

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Felgner, Sebastian, Frahm, Michael, Kocijancic, Dino, Rohde, Manfred, Eckweiler, Denitsa, Bielecka, Agata, Bueno, Emilio, Cava, Felipe, Abraham, Wolf-Rainer, Curtiss, Roy, Häussler, Susanne, Erhardt, Marc, Weiss, Siegfried
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013297/
https://ncbi.nlm.nih.gov/pubmed/27601574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01220-16
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