aroA-Deficient Salmonella enterica Serovar Typhimurium Is More Than a Metabolically Attenuated Mutant

Recombinant attenuated Salmonella enterica serovar Typhimurium strains are believed to act as powerful live vaccine carriers that are able to elicit protection against various pathogens. Auxotrophic mutations, such as a deletion of aroA, are commonly introduced into such bacteria for attenuation wit...

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Publicat a:mBio
Autors principals: Felgner, Sebastian, Frahm, Michael, Kocijancic, Dino, Rohde, Manfred, Eckweiler, Denitsa, Bielecka, Agata, Bueno, Emilio, Cava, Felipe, Abraham, Wolf-Rainer, Curtiss, Roy, Häussler, Susanne, Erhardt, Marc, Weiss, Siegfried
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013297/
https://ncbi.nlm.nih.gov/pubmed/27601574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01220-16
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