Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response

Given the high costs of conducting a drug-response trial, researchers are now aiming to use retrospective analyses to conduct genome-wide association studies (GWAS) to identify underlying genetic contributions to drug-response variation. To prevent confounding results from a GWAS to investigate drug...

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Udgivet i:Front Genet
Main Authors: Graham, Hillary T., Rotroff, Daniel M., Marvel, Skylar W., Buse, John B., Havener, Tammy M., Wilson, Alyson G., Wagner, Michael J., Motsinger-Reif, Alison A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013254/
https://ncbi.nlm.nih.gov/pubmed/27775101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00138
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