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The Entangled ER-Mitochondrial axis as a potential therapeutic strategy in Neurodegeneration: A Tangled Duo Unchained

Endoplasmic reticulum (ER) and mitochondrial function have both been shown to be critical events in neurodegenerative diseases. The ER mediates protein folding, maturation, sorting as well acts as calcium storage. The unfolded protein response (UPR) is a stress response of the ER that is activated b...

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Bibliografiset tiedot
Julkaisussa:Cell Calcium
Päätekijät: Joshi, Amit U., Kornfeld, Opher S., Mochly-Rosen, Daria
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012927/
https://ncbi.nlm.nih.gov/pubmed/27212603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2016.04.010
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