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The Entangled ER-Mitochondrial axis as a potential therapeutic strategy in Neurodegeneration: A Tangled Duo Unchained

Endoplasmic reticulum (ER) and mitochondrial function have both been shown to be critical events in neurodegenerative diseases. The ER mediates protein folding, maturation, sorting as well acts as calcium storage. The unfolded protein response (UPR) is a stress response of the ER that is activated b...

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Detalhes bibliográficos
Publicado no:Cell Calcium
Main Authors: Joshi, Amit U., Kornfeld, Opher S., Mochly-Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012927/
https://ncbi.nlm.nih.gov/pubmed/27212603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2016.04.010
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