A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer

BACKGROUND & AIMS: The lack of a preclinical model of progressive non-alcoholic steatohepatitis (NASH) that recapitulates human disease is a barrier to therapeutic development. METHODS: A stable isogenic cross between C57BL/6J (B6) and 129S1/SvImJ (S129) mice were fed a high fat diet with ad lib...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Asgharpour, Amon, Cazanave, Sophie C., Pacana, Tommy, Seneshaw, Mulugeta, Vincent, Robert, Banini, Bubu A., Kumar, Divya Prasanna, Daita, Kalyani, Min, Hae-Ki, Mirshahi, Faridoddin, Bedossa, Pierre, Sun, Xiaochen, Hoshida, Yujin, Koduru, Srinivas V., Contaifer, Daniel, Warncke, Urszula Osinska, Wijesinghe, Dayanjan S., Sanyal, Arun J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012902/
https://ncbi.nlm.nih.gov/pubmed/27261415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.05.005
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