Deletion of African swine fever virus interferon inhibitors from the genome of a virulent isolate reduces virulence in domestic pigs and induces a protective response

African swine fever virus (ASFV) encodes multiple copies of MGF360 and MGF530/505 gene families. These genes have been implicated in the modulation of the type I interferon (IFN) response. We investigated the effect of modulating the IFN response on virus attenuation and induction of protective immu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Reis, Ana Luisa, Abrams, Charles C., Goatley, Lynnette C., Netherton, Chris, Chapman, Dave G., Sanchez-Cordon, Pedro, Dixon, Linda K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012891/
https://ncbi.nlm.nih.gov/pubmed/27521231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.08.011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados