Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge

Many of the approximately 165 proteins encoded by the African swine fever virus (ASFV) genome do not have significant similarity to known proteins and have not been studied experimentally. One such protein is DP148R. We showed that the DP148R gene is transcribed at early times postinfection. Deletio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Reis, Ana L., Goatley, Lynnette C., Jabbar, Tamara, Sanchez-Cordon, Pedro J., Netherton, Christopher L., Chapman, David A. G., Dixon, Linda K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Pathogenesis and Immunity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709585/
https://ncbi.nlm.nih.gov/pubmed/28978700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01428-17
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