Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge

Many of the approximately 165 proteins encoded by the African swine fever virus (ASFV) genome do not have significant similarity to known proteins and have not been studied experimentally. One such protein is DP148R. We showed that the DP148R gene is transcribed at early times postinfection. Deletio...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Reis, Ana L., Goatley, Lynnette C., Jabbar, Tamara, Sanchez-Cordon, Pedro J., Netherton, Christopher L., Chapman, David A. G., Dixon, Linda K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709585/
https://ncbi.nlm.nih.gov/pubmed/28978700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01428-17
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