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Cardiac action of the first G protein biased small molecule apelin agonist
Apelin peptide analogues displaying bias towards G protein signalling pathways have beneficial cardiovascular actions compared with the native peptide in humans in vivo. Our aim was to determine whether small molecule agonists could retain G protein bias. We have identified a biased small molecule,...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012889/ https://ncbi.nlm.nih.gov/pubmed/27475715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.07.018 |
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