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Isoegomaketone Upregulates Heme Oxygenase-1 in RAW264.7 Cells via ROS/p38 MAPK/Nrf2 Pathway

Isoegomaketone (IK) was isolated from Perilla frutescens, which has been widely used as a food in Asian cuisine, and evaluated for its biological activity. We have already confirmed that IK induced the HO-1 expression via Nrf2 activation in RAW264.7 cells. In this study, we investigated the effect o...

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Publicado en:Biomol Ther (Seoul)
Autores principales: Jin, Chang Hyun, So, Yang Kang, Han, Sung Nim, Kim, Jin-Baek
Formato: Artigo
Lenguaje:Inglês
Publicado: The Korean Society of Applied Pharmacology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012876/
https://ncbi.nlm.nih.gov/pubmed/27582555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.194
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