YJI-7 Suppresses ROS Production and Expression of Inflammatory Mediators via Modulation of p38MAPK and JNK Signaling in RAW 264.7 Macrophages

Chalcone, (2E)-1,3-Diphenylprop-2-en-1-one, and its synthetic derivatives are known to possess anti-oxidative and anti-inflammatory properties. In the present study, we prepared a novel synthetic chalcone compound, (E)-1-(4-hydroxyphenyl)-3-(2-(trifluoromethoxy)phenyl)prop-2-en-1-one name (YJI-7), a...

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Bibliografiske detaljer
Udgivet i:Biomol Ther (Seoul)
Main Authors: Oh, Hye Jin, Magar, Til Bahadur Thapa, Pun, Nirmala Tilija, Lee, Yunji, Kim, Eun Hye, Lee, Eung-Seok, Park, Pil-Hoon
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Society of Applied Pharmacology 2018
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839498/
https://ncbi.nlm.nih.gov/pubmed/28441795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.276
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