Limited Generalizability of Registration Trials in Hepatitis C: A Nationwide Cohort Study

BACKGROUND: Approval of drugs in chronic hepatitis C is supported by registration trials. These trials might have limited generalizability through use of strict eligibility criteria. We compared effectiveness and safety of real world hepatitis C patients eligible and ineligible for registration tria...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Berden, Floor A. C., de Knegt, Robert J., Blokzijl, Hans, Kuiken, Sjoerd D., van Erpecum, Karel J. L., Willemse, Sophie B., den Hollander, Jan, van Vonderen, Marit G. A., Friederich, Pieter, van Hoek, Bart, van Nieuwkerk, Carin M. J., Drenth, Joost P. H., Kievit, Wietske
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012685/
https://ncbi.nlm.nih.gov/pubmed/27598789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161821
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