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Drug holiday in patients with polycystic liver disease treated with somatostatin analogues

BACKGROUND: Somatostatin analogues (SAs) reduce liver volume and relief symptoms in polycystic liver disease (PLD). Its effect wears off after continuing therapy suggesting development of SA tolerance in patients on chronic therapy. We postulate that a drug holiday resensitizes the liver to its acut...

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Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: van Aerts, René M. M., Kolkman, Marieke, Kievit, Wietske, Gevers, Tom J. G., Nevens, Frederik, Drenth, Joost P. H.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172936/
https://ncbi.nlm.nih.gov/pubmed/30302127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284818804784
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