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Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex

The N-terminal 34-amino-acid peptide fragment of human parathyroid hormone PTH (1-34), is used clinically to treat osteoporosis; however, it is currently administered by a once-daily subcutaneous injection, resulting in poor patient compliance. We have developed enteric microcapsules containing an i...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Hwang, Seung Rim, Seo, Dong-Hyun, Byun, Youngro, Park, Jin Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012625/
https://ncbi.nlm.nih.gov/pubmed/27621618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S110573
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