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Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex
The N-terminal 34-amino-acid peptide fragment of human parathyroid hormone PTH (1-34), is used clinically to treat osteoporosis; however, it is currently administered by a once-daily subcutaneous injection, resulting in poor patient compliance. We have developed enteric microcapsules containing an i...
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Published in: | Int J Nanomedicine |
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Main Authors: | , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
Dove Medical Press
2016
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012625/ https://ncbi.nlm.nih.gov/pubmed/27621618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S110573 |
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