Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice

Adipose tissue macrophage (ATM)-mediated inflammation is a key feature contributing to the adverse metabolic outcomes of dietary obesity. Recruitment of macrophages to obese adipose tissues (AT) can occur through the engagement of CCR2, the receptor for MCP-1 (monocyte chemoattractant protein-1), wh...

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Publicat a:Mol Ther Nucleic Acids
Autors principals: Kim, Jongkil, Chung, Kunho, Choi, Changseon, Beloor, Jagadish, Ullah, Irfan, Kim, Nahyeon, Lee, Kuen Yong, Lee, Sang-Kyung, Kumar, Priti
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012549/
https://ncbi.nlm.nih.gov/pubmed/26812653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.51
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