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Ubiquitin-Conjugating Enzyme 9 Phosphorylation as a Novel Mechanism for Potentiation of the Inflammatory Response

Lipopolysaccharide (LPS), a bacterial endotoxin, induces inflammation in macrophages via activation of NF-κB signaling. Sumoylation is a post-translational modification mediated by the small ubiquitin-like modifier, SUMO. Ubiquitin-conjugating enzyme 9 (UBC9) is the only known SUMO conjugating enzym...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Tomasi, Maria Lauda, Ramani, Komal, Ryoo, Minjung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012469/
https://ncbi.nlm.nih.gov/pubmed/27561301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.05.007
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