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ROLE OF METHIONINE ADENOSYLTRANSFERASE α2 AND β PHOSPHORYLATION AND STABILIZATION IN HUMAN HEPATIC STELLATE CELL TRANS-DIFFERENTIATION

Myofibroblastic trans-differentiation of hepatic stellate cells (HSCs) is an essential event in the development of liver fibrogenesis. These changes involve modulation of key regulators of the genome and the proteome. Methionine adenosyltransferases (MAT) catalyze the biosynthesis of the methyl dono...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Ramani, Komal, Donoyan, Shant, Tomasi, Maria Lauda, Park, Sunhee
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839286/
https://ncbi.nlm.nih.gov/pubmed/25294683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24839
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