ROLE OF METHIONINE ADENOSYLTRANSFERASE α2 AND β PHOSPHORYLATION AND STABILIZATION IN HUMAN HEPATIC STELLATE CELL TRANS-DIFFERENTIATION

Myofibroblastic trans-differentiation of hepatic stellate cells (HSCs) is an essential event in the development of liver fibrogenesis. These changes involve modulation of key regulators of the genome and the proteome. Methionine adenosyltransferases (MAT) catalyze the biosynthesis of the methyl dono...

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Udgivet i:J Cell Physiol
Main Authors: Ramani, Komal, Donoyan, Shant, Tomasi, Maria Lauda, Park, Sunhee
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839286/
https://ncbi.nlm.nih.gov/pubmed/25294683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24839
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