ROLE OF METHIONINE ADENOSYLTRANSFERASE α2 AND β PHOSPHORYLATION AND STABILIZATION IN HUMAN HEPATIC STELLATE CELL TRANS-DIFFERENTIATION

Myofibroblastic trans-differentiation of hepatic stellate cells (HSCs) is an essential event in the development of liver fibrogenesis. These changes involve modulation of key regulators of the genome and the proteome. Methionine adenosyltransferases (MAT) catalyze the biosynthesis of the methyl dono...

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Publié dans:J Cell Physiol
Auteurs principaux: Ramani, Komal, Donoyan, Shant, Tomasi, Maria Lauda, Park, Sunhee
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839286/
https://ncbi.nlm.nih.gov/pubmed/25294683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24839
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