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In vivo conformational dynamics of Hsp90 and its interactors

Hsp90 belongs to a family of some of the most highly expressed heat shock proteins that function as molecular chaperones to protect the proteome not only from the heat shock, but from other misfolding events. As many client proteins of Hsp90 are involved in oncogenesis, this chaperone has been in fo...

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Publicat a:Cell Chem Biol
Autors principals: Chavez, Juan D., Schweppe, Devin K., Eng, Jimmy K., Bruce, James E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012217/
https://ncbi.nlm.nih.gov/pubmed/27341434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.05.012
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