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Application of the Protein Semisynthesis Strategy to the Generation of Modified Chromatin

Histone proteins are subject to a host of posttranslational modifications (PTMs) that modulate chromatin structure and function. Such control is achieved by the direct alteration of the intrinsic physical properties of the chromatin fiber or by regulating the recruitment and activity of a host of tr...

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Detalhes bibliográficos
Publicado no:Annu Rev Biochem
Main Authors: Holt, Matthew, Muir, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011971/
https://ncbi.nlm.nih.gov/pubmed/25784050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-060614-034429
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