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Application of the Protein Semisynthesis Strategy to the Generation of Modified Chromatin

Histone proteins are subject to a host of posttranslational modifications (PTMs) that modulate chromatin structure and function. Such control is achieved by the direct alteration of the intrinsic physical properties of the chromatin fiber or by regulating the recruitment and activity of a host of tr...

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Dettagli Bibliografici
Pubblicato in:Annu Rev Biochem
Autori principali: Holt, Matthew, Muir, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011971/
https://ncbi.nlm.nih.gov/pubmed/25784050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-060614-034429
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