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Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

Disruptions to genes linked to RNA processing and homeostasis are implicated in the pathogenesis of two pathologically related but clinically heterogeneous neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Mutations in the Fused-in-Sarcoma (FUS) gene...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Nolan, Matthew, Talbot, Kevin, Ansorge, Olaf
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011941/
https://ncbi.nlm.nih.gov/pubmed/27600654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0358-8
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