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Pathogenesis of FUS-associated ALS and FTD: insights from rodent models

Disruptions to genes linked to RNA processing and homeostasis are implicated in the pathogenesis of two pathologically related but clinically heterogeneous neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Mutations in the Fused-in-Sarcoma (FUS) gene...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Nolan, Matthew, Talbot, Kevin, Ansorge, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011941/
https://ncbi.nlm.nih.gov/pubmed/27600654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0358-8
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