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Protein Allostery and Conformational Dynamics

The functions of many proteins are regulated through allostery, whereby effector binding at a distal site changes the functional activity (e.g., substrate binding affinity or catalytic efficiency) at the active site. Most allosteric studies have focused on thermodynamic properties, in particular, su...

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Detalhes bibliográficos
Publicado no:Chem Rev
Main Authors: Guo, Jingjing, Zhou, Huan-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011433/
https://ncbi.nlm.nih.gov/pubmed/26876046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00590
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