Ganglioside GM3 synthase depletion reverses neuropathic pain and small fiber neuropathy in diet-induced diabetic mice

BACKGROUND: Small fiber neuropathy is a well-recognized complication of type 2 diabetes and has been shown to be responsible for both neuropathic pain and impaired wound healing. In previous studies, we have demonstrated that ganglioside GM3 depletion by knockdown of GM3 synthase fully reverses impa...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Menichella, Daniela M, Jayaraj, Nirupa D, Wilson, Heather M, Ren, Dongjun, Flood, Kelsey, Wang, Xiao-Qi, Shum, Andrew, Miller, Richard J, Paller, Amy S
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011393/
https://ncbi.nlm.nih.gov/pubmed/27590073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916666284
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