IL-12 signals through the TCR to support CD8 innate immune responses

CD8 T cells must integrate antigenic and inflammatory signals to differentiate into efficient effector and memory T cells able to protect us from infections. The mechanisms by which T cell receptor (TCR) signaling and pro-inflammatory cytokine receptor signaling cooperate in these processes are poor...

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Udgivet i:J Immunol
Main Authors: Goplen, Nicholas P., Saxena, Vikas, Knudson, Karin M., Schrum, Adam G., Gil, Diana, Daniels, Mark A., Zamoyska, Rose, Teixeiro, Emma
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010952/
https://ncbi.nlm.nih.gov/pubmed/27521342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600037
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