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Members of the Hsp70 family recognize distinct types of sequences to execute ER quality control

Protein maturation in the endoplasmic reticulum is controlled by multiple chaperones, but how they recognize and determine the fate of their clients remains unclear. We developed an in vivo peptide library covering substrates of the ER Hsp70 system: BiP, Grp170, and three of BiP’s DnaJ-family co-fac...

詳細記述

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書誌詳細
出版年:Mol Cell
主要な著者: Behnke, Julia, Mann, Melissa J., Scruggs, Fei-Lin, Feige, Matthias J., Hendershot, Linda M.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010498/
https://ncbi.nlm.nih.gov/pubmed/27546788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.012
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