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The Large Hsp70 Grp170 Binds to Unfolded Protein Substrates in Vivo with a Regulation Distinct from Conventional Hsp70s

The Hsp70 superfamily is a ubiquitous chaperone class that includes conventional and large Hsp70s. BiP is the only conventional Hsp70 in the endoplasmic reticulum (ER) whose functions include: assisting protein folding, targeting misfolded proteins for degradation, and regulating the transducers of...

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Bibliografiske detaljer
Main Authors: Behnke, Julia, Hendershot, Linda M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908422/
https://ncbi.nlm.nih.gov/pubmed/24327659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507491
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