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Members of the Hsp70 family recognize distinct types of sequences to execute ER quality control

Protein maturation in the endoplasmic reticulum is controlled by multiple chaperones, but how they recognize and determine the fate of their clients remains unclear. We developed an in vivo peptide library covering substrates of the ER Hsp70 system: BiP, Grp170, and three of BiP’s DnaJ-family co-fac...

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Publicado en:Mol Cell
Autores principales: Behnke, Julia, Mann, Melissa J., Scruggs, Fei-Lin, Feige, Matthias J., Hendershot, Linda M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010498/
https://ncbi.nlm.nih.gov/pubmed/27546788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.012
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