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Members of the Hsp70 family recognize distinct types of sequences to execute ER quality control
Protein maturation in the endoplasmic reticulum is controlled by multiple chaperones, but how they recognize and determine the fate of their clients remains unclear. We developed an in vivo peptide library covering substrates of the ER Hsp70 system: BiP, Grp170, and three of BiP’s DnaJ-family co-fac...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010498/ https://ncbi.nlm.nih.gov/pubmed/27546788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.012 |
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