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A Hybrid Drug Limits Resistance by Evading the Action of the Multiple Antibiotic Resistance Pathway
Hybrid drugs are a promising strategy to address the growing problem of drug resistance, but the mechanism by which they modulate the evolution of resistance is poorly understood. Integrating high-throughput resistance measurements and genomic sequencing, we compared Escherichia coli populations evo...
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| Publicado no: | Mol Biol Evol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009991/ https://ncbi.nlm.nih.gov/pubmed/26538141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv243 |
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