Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Adrenocorticotropic Hormone Production and Tumorous Corticotroph Cell Growth in AtT20 Cells

BACKGROUND: Two recent whole-exome sequencing researches identifying somatic mutations in the ubiquitin-specific protease 8 (USP8) gene in pituitary corticotroph adenomas provide exciting advances in this field. These mutations drive increased epidermal growth factor receptor (EGFR) signaling and pr...

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Detalhes bibliográficos
Publicado no:Chin Med J (Engl)
Main Authors: Jian, Fang-Fang, Li, Yun-Feng, Chen, Yu-Fan, Jiang, Hong, Chen, Xiao, Zheng, Li-Li, Zhao, Yao, Wang, Wei-Qing, Ning, Guang, Bian, Liu-Guan, Sun, Qing-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009596/
https://ncbi.nlm.nih.gov/pubmed/27569239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.189047
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