Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of T-cell malignancies that generally demonstrate aggressive clinical behavior, often are refractory to standard therapy, and remain significantly understudied. The most common World Health Organization subtype is PTCL, not otherwis...

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Vydáno v:Blood
Hlavní autoři: Boddicker, Rebecca L., Razidlo, Gina L., Dasari, Surendra, Zeng, Yu, Hu, Guangzhen, Knudson, Ryan A., Greipp, Patricia T., Davila, Jaime I., Johnson, Sarah H., Porcher, Julie C., Smadbeck, James B., Eckloff, Bruce W., Billadeau, Daniel D., Kurtin, Paul J., McNiven, Mark A., Link, Brian K., Ansell, Stephen M., Cerhan, James R., Asmann, Yan W., Vasmatzis, George, Feldman, Andrew L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009513/
https://ncbi.nlm.nih.gov/pubmed/27297792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-707141
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