Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase.

Conditional expression of wild-type (wt) p53 protein in a glioblastoma tumor cell line has been shown to be growth inhibitory. We have now more precisely localized the position in the cell cycle where growth arrest occurs. We show that growth arrest occurs prior to or near the restriction point in l...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Lin, D, Shields, M T, Ullrich, S J, Appella, E, Mercer, W E
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9210
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