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Enhanced pinocembrin production in Escherichia coli by regulating cinnamic acid metabolism
Microbial biosynthesis of pinocembrin is of great interest in the area of drug research and human healthcare. Here we found that the accumulation of the pathway intermediate cinnamic acid adversely affected pinocembrin production. Hence, a stepwise metabolic engineering strategy was carried out aime...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009306/ https://ncbi.nlm.nih.gov/pubmed/27586788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32640 |
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