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Enhanced pinocembrin production in Escherichia coli by regulating cinnamic acid metabolism
Microbial biosynthesis of pinocembrin is of great interest in the area of drug research and human healthcare. Here we found that the accumulation of the pathway intermediate cinnamic acid adversely affected pinocembrin production. Hence, a stepwise metabolic engineering strategy was carried out aime...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009306/ https://ncbi.nlm.nih.gov/pubmed/27586788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32640 |
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